Abstracts
Association between self-efficacy and health-related quality of life in Intensive Care COVID-19-survivors, the prospective MaastrICCht cohort
Inhoud:

    Auteur(s):

    Laura Tiels1, Marieke Wintjens1,  Sophie Waardenburg2, Frank van Rosmalen1, Sander van Kuijk2, Iwan van der Horst1, Regien Luiten1, Bea Hemmen3, Bas van Bussel1, Walther van Mook1, Susanne van Santen1

     

    1Department of Intensive Care Medicine, Maastricht University Medical Centre+, Maastricht University, Maastricht, the Netherlands

    2Department of Clinical Epidemiology and Medical Technology Assessment (KEMTA), Maastricht University, Maastricht, the Netherlands

    3Department of Rehabilitation, Maastricht University Medical Centre+, Maastricht University, Maastricht, the Netherlands
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    Abstracts

    Association between self-efficacy and health-related quality of life in Intensive Care COVID-19-survivors, the prospective MaastrICCht cohort

    Teaser: In een cohort van COVID-19 overlevenden onderzochten we de associatie tussen zelfeffectiviteit, gemeten met GSES 3 maanden na ontslag, en kwaliteit van leven (KvL), gemeten met EQ-5D-5L op 3, 12 en 24 maanden na ontslag. Hogere zelfeffectiviteit bleek geassocieerd met hogere KvL tot twee jaar na ontslag. Dit suggereert dat verbeteren van zelfeffectiviteit een potentieel aangrijpingspunt is na IC-ontslag.

    Background: The health-related quality of life (HRQoL) of Intensive Care Unit (ICU) survivors may be severely impacted long-term after their ICU admission. Our hypothesis is that the level of self-efficacy may influence HRQoL of ICU survivors. This association may have therapeutic implications. In a cohort of COVID-19 survivors, we investigated the association between self-efficacy, 3 months after ICU discharge, and HRQoL at 3, 12 and 24 months after ICU discharge.

    Methods: The prospective Maastricht Intensive Care COVID cohort (MaastrICCht) includes COVID-19 patients admitted to the ICU between March 2020 and April 2021. All patients that visited the post-ICU clinic were included in the present study. Self-efficacy was assessed at 3 months using the General Self-Efficacy Scale (GSES). HRQoL was measured using the EuroQol 5 Dimensions 5 Levels (EQ-5D-5L) at 3, 12 and 24 months, subdivided in a health utility score (EQ-HUS) and visual analogue scale (EQ-VAS). We used linear regression to investigate the association between self-efficacy and EQ-5D-5L and report regression coefficients with 95% confidence interval (CI).

    Results: A total of 92 ICU survivors were included. Patient-reported outcomes showed a mean score of the total GSES of 30.7 ± 7.4 at 3 months. At 3-, 12- and 24-month follow-up, the mean score for the EQ-HUS was 0.67, 0.82 and 0.83, respectively. For the EQ-VAS, the mean score was 60.9, 74.7 and 69.7, respectively. Higher self-efficacy at 3 months was associated with higher a EQ-HUS at 3 months (β=0.02; 95% CI: 0.01–0.02), 12 months (β=0.01; 95% CI: 0.01-0.02) and 24 months (β=0.01; 95% CI: 0.00-0.02). Higher self-efficacy at 3 months was also associated with a higher EQ-VAS at 3 months (β=1.21; 95% CI: 0.77-1.65), 12 months (β=0.81; 95% CI: 0.21-1.42) and 24 months (β=0.75; 95% CI: 0.03-1.46).

    Conclusions: Higher self-efficacy at 3 months after ICU discharge is associated with higher HRQL up to two years after ICU discharge in COVID-19 survivors. This suggests that interventions to improve self-efficacy appears a potential target post-ICU to enhance quality of life over the long term.