Volume 30

At least he didn’t miss his train…

24 november 2022

Case A 35-year-old male presented to the emergency room (ER) with acute dyspnoea (SpO2 98%), pain and absent breathing sounds over the left hemithorax and hypotension (reported pre-hospital blood pressure 63/37 mmHg). He had no relevant medical history, except smoking of marihuana. Supposedly he felt a little snap in the…

Treat the lungs and wait for the brain in COVID-19: a case report of severe COVID-19 encephalopathy

24 november 2022

Abstract Encephalopathy is a severe and underestimated neurological complication of COVID-19 infection, with a high prevalence in COVID-19 patients in intensive care. We present a case of a 68-year-old male with severe COVID-19 encephalopathy and prolonged lowered consciousness, without showing any brain imaging abnormalities. There are multiple mechanisms of cause,…

An 85-year old patient with severe ongoing bleeding

24 november 2022

Abstract In this case report, we describe an 85-year-old female patient who presented with a rare but important problem of anticoagulant rebound complicating dabigatran use. Despite multiple attempts to correct the bleeding, it continued and the coagulation times remained prolonged. Important risk factors for high dabigatran concentrations and prolonged coagulation…

What is this CVVHD device telling you about your patient?

24 november 2022

A 74-year-old man was admitted to the haematology ward because of acute promyelocytic leukaemia and treated with all-trans retinoic acid and arsenic trioxide. Treatment was complicated by differentiation syndrome. The patient developed progressive respiratory failure caused by herpes simplex virus pneumonia. Following admission to the intensive care unit, he was…

Potential pandemic pathogens series: Ebola virus

24 november 2022

History of Ebola virus Ebolavirus (EBOV) is a member of the family of the Filoviridae together with five other genera: Marburgvirus, Cuevavirus, Dianlovirus, Striavirus and Thamnovirus. Importantly, novel filoviruses of unknown pathogenic potential continue to be discovered by global surveillance programs. Filoviridae are filamentous virions containing a negative sense RNA…

With our minds wide open: Let us foster the young academic spirit in critical care!

24 november 2022

In this last issue of the Netherlands Journal of Critical Care (NJCC) in 2022, Ronald Akkerman and colleagues from the Leiden University Medical Center review the Ebola virus in the series of potential pandemic pathogens.[1] As many among us contemplate the possible impact of the coronavirus disease of 2019 (COVID-19)…

Volume 30, Issue 6 – November 2022

24 november 2022

Forecast with eyes wide open – a perspective on the upcoming winter

22 september 2022

Since the onset of the coronavirus disease of 2019 (COVID-19) pandemic, many patients have become infected. In addition, many have been admitted to intensive care due to the severity of the disease, exacerbated comorbidities or new diseases occurring concomitantly with COVID-19. Whether the upcoming winter will be challenging is currently…

Volume 30, Issue 5 – September 2022

22 september 2022

Vaccine-induced thrombotic thrombocytopenia with saddle pulmonary embolism, a therapeutic challenge

01 september 2022

Case A 63-year-old woman was brought to the emergency department because of chest pain, severe dyspnoea and syncope. She had been experiencing abdominal discomfort and vomiting since her vaccination with ChAdOx1 nCoV-19 (AstraZeneca) 12 days earlier. Her past medical history included a cholecystectomy and a deep venous thrombosis of the…