Issue 2 – March 2022
Abstract Objective: To develop and validate a clinical prediction model to estimate the probability of extubation failure (EF) in the intensive care unit (ICU). Methods: An observational, analytical, prospective cohort study was conducted to derive and validate a clinical prediction model and a risk prediction score for EF. The study…
Abstract Methaemoglobinaemia is a rare complication of prilocaine, mainly affecting individuals with predisposing conditions or those receiving an unusually high dose. However, this case shows that a predetermined safe dose of prilocaine can still produce clinically significant symptoms. A healthy 20-year-old female presented with cyanosis, tachycardia and a low oxygen…
A pandemic is an epidemic of an infectious disease which has spread across a substantial part of the world and affects a large number of individuals.[1] Throughout history the world has constantly suffered from pandemics. As humanity started out as hunter gatherers, the interactions with other humans and animals was…
Case A 68-year-old man with a medical history of type 2 diabetes, obstructive sleep apnoea, back pain for which oxycodone was prescribed, and absolute canal stenosis with claudication was admitted to the intensive care unit (ICU) due to a reduced level of consciousness and hypoventilation because of autointoxication. In the…
Abstract Diabetic ketoacidosis (DKA) is a severe and potentially lethal complication of diabetes. The use of a relatively new class of antihyperglycaemic drugs, the SGLT2 inhibitors, can cause DKA, albeit with a different presentation compared to the ‘classic’ DKA. Therefore, since it might not be recognised at an early stage,…
In the last two years we have experienced the effects of the COVID-19 pandemic in our lives and hospitals. Pandemics are part of the history of humanity and we can be certain that in the future new pandemics will appear. In fact, due to the growth in the human population,…