Original Article
Abstract Background: Sepsis is a life-threatening syndrome for which early recognition and treatment are essential to improve clinical outcomes yet it is not known how…
Abstract In this paper we describe how the data infrastructure of an existing national quality registry was adapted to meet public health, research and capacity…
Abstract Background: In several countries, the advanced practice provider (APP) is positioned as a clinician in an acute care setting. In the Netherlands, physician assistants…
Abstract Background: Continuous renal replacement therapy in the treatment of patients with active COVID-19 is frequently complicated by thrombosis in the extracorporeal circuit resulting in…
Abstract Objective: To develop and validate a clinical prediction model to estimate the probability of extubation failure (EF) in the intensive care unit (ICU). Methods:…
Abstract Last year the global community was confronted with COVID-19, a rapidly spreading pandemic disease. Hospitals had to cope with an increasing number of infectious…
Abstract Background: The COVID-19 pandemic has overwhelmed healthcare systems all over the world. Many countries have formulated guidelines for a scenario in which ICU triage…
Abstract Background: Intensive care patients often suffer from short, fragmented and low-quality sleep. Poor sleep can cause prolonged mechanical ventilation, delirium and deranged metabolic function.…
Abstract Purpose: Transfusing red blood cells (RBCs) in non-bleeding critically ill patients once the haemoglobin meets a certain threshold is the standard of care, despite…
Abstract Background: Rapid response systems (RRSs) have been introduced to assist in the effective management of deteriorating patients. Optimal system performance requires adequate staffing levels…
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