Volume 30, Issue 3 – May 2022

Cover - Volume 30 Issue 3

Voriconazole for pulmonary aspergillosis: a case report underlining the necessity of drug monitoring

Abstract Voriconazole is commonly used for the treatment of invasive pulmonary aspergillosis. Recent guidelines strongly advise routine therapeutic drug monitoring for patients receiving voriconazole. We present a case with subtherapeutic voriconazole serum levels caused by…

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Frequent CRRT circuit failure in COVID-19: observations of a novel anticoagulation approach

Abstract Background: Continuous renal replacement therapy in the treatment of patients with active COVID-19 is frequently complicated by thrombosis in the extracorporeal circuit resulting in reduced filter lifespan, necessitating a revisited anticoagulation strategy. Methods: The…

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Postoperative graft spasm after coronary artery bypass surgery in a patient with hyperparathyroidism

Abstract We present the case of a 70-year-old man who developed postoperative graft spasm after coronary artery bypass surgery, which was successfully treated with calcium channel blockers. An elevated ionised calcium was found and subsequently…

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Organ donation after euthanasia in the Netherlands

Abstract Organ donation after euthanasia is performed in the Netherlands, Belgium, Spain and Canada. In these countries, altruistic patients, who often suffer from a neurodegenerative or psychiatric disease, are able to donate their lungs, liver,…

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Rescue plasmapheresis for massive shear stress-induced haemolysis following paravalvular leak closure

Abstract Given the increasing use of transcatheter (para)valvular interventions and mechanical circulatory support, haemolysis is becoming a more frequently encountered complication. In this setting, patients should be actively monitored for signs of haemolysis, given the…

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Organ donation after euthanasia in the Netherlands: valuable or costly?

It has been 10 years since the first organ donation after euthanasia (ODE) was performed in the Netherlands. Since then, many procedures have been carried out and we have learned about the possibilities and potential…

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Potential pandemic pathogens series: Nipah virus

In the last two years we have experienced the effects of the COVID-19 pandemic in our lives and hospitals. Pandemics are part of the history of humanity and we can be certain that in the…

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